New non-hormonal hot flush drugs: fezolinetant and elinzanetant
For the first time there are drugs that stop hot flushes at the source in the brain without using hormones. How they work, what the trials found, and who they might suit.
Journal · topic
New papers, new drugs and updated guidelines, explained in everyday language.
For the first time there are drugs that stop hot flushes at the source in the brain without using hormones. How they work, what the trials found, and who they might suit.
"Your bloods are normal" is one of the most common and least helpful sentences in perimenopause. A single hormone reading can't settle the question. This explains why, and which tests are worth asking for.
Stiff hands in the morning, a shoulder that will not lift, knees that complain on the stairs. In 2024 researchers proposed a name for this cluster and made the case that it is hormonal.
"It'll pass" is not a plan. The SWAN study followed thousands of women for decades and put numbers on how long the transition, and its symptoms, really last.
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